A motorcyclist is believed to be seriously injured after a crash on the Huon Highway.
Police and emergency services were called to the scene near Sandfly at around 8:15am this morning.
The incident involves a yellow Triumph motorcycle and a white Isuzu truck, initial investigations indicating the motorcycle collided with the rear of the truck.
The 22-year-old rider has been taken to hospital, while the 40-year-old man driving the truck was not physically injured.
The right-hand lane of the highway was closed for 3 hours this morning to allow crash investigators to examine the scene and conduct inquiries.
Police are asking anyone with information or relevant dash cam footage to come forward and call Crime Stoppers on 1800 333 000.
You can remain anonymous.