Public Health are monitoring quarantined Spirit of Tasmania crew members closely, after they were identified as primary close contacts of a positive COVID-19 case.
Friday night's scheduled sailing had been put on hold after a Melbourne-based TT-Line contractor became infected with Coronavirus.
17 primary close contacts have been found; all are operational crew members who do not have contact with passengers.
Nine of these contacts were taken from the ship and placed into hotel quarantine for testing and 14 days of isolation.
Another two primary close contacts were found overnight; all are quarantining.
All 11 close contacts have so far returned negative test results.
Six Victorian crew members have also been identified as primary close contacts, two of them returning negative results so far.
The ferries will sail from Devonport and Melbourne when more of those test results come back.
Public Health has stressed the risk to passengers is "very, very low".
TT-Line CEO Bernard Dwyer says they'll be doing "everything they can to minimise disruptions for travellers"
"The policy of TT-Line from day one of COVID from March last year was anybody who has been impacted by COVID has a full refund of their fare; and there's no charges in relation to changing a booking or moving bookings as well".
Premier Peter Gutwein says this very situation is a demonstration that Tasmanian systems are working.